Difference between revisions of "Risk factors for severe disease"
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| + | * Recent studies suggest that ACE2 expression is increased in diabetes and treatment with ACE inhibitors and ARBs increases ACE2 expression. Consequently, the increased expression of ACE2 would facilitate infection with COVID-19. This observation makes some researchers hypothesize that diabetes and hypertension treatment with ACE2-stimulating drugs increases the risk of developing severe and fatal COVID-19. <ref name="Fang2020">Fang, Lei, George Karakiulakis, and Michael Roth. "Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?." The Lancet Respiratory Medicine (2020).</ref> | ||
=Rumours about interaction with medicines= | =Rumours about interaction with medicines= | ||
Revision as of 20:49, 16 March 2020
This page collects observations, interpretations, and consequences for action about Risk Factors of SARS-CoV2. Please observe the structure of the page, when you add your content. Please use references where possible. Remember to find the relevant page. For example, if your observation is about Sources, please use that page, instead of posting your content here.
Contents
What is already known
- Recent studies suggest that ACE2 expression is increased in diabetes and treatment with ACE inhibitors and ARBs increases ACE2 expression. Consequently, the increased expression of ACE2 would facilitate infection with COVID-19. This observation makes some researchers hypothesize that diabetes and hypertension treatment with ACE2-stimulating drugs increases the risk of developing severe and fatal COVID-19. [1]
Rumours about interaction with medicines
Observations
- Some people worry about the news that some drugs make you more susceptible to severe disease. Questions that health practitioner struggle with:
- what evidence we have?
- what do we say to people?
Analysis and interpretation
- how can we avoid the spreading of fake news that can lead people to unsafe practices such as stop taking drugs for hypertension to avoid covid 19?
Consequences for action
- We need to monitor this kind of rumors and address them
References
- ↑ Fang, Lei, George Karakiulakis, and Michael Roth. "Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?." The Lancet Respiratory Medicine (2020).