Transmission routes

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This page collects observations, interpretations, and consequences for action about Transmission Routes of SARS-CoV2. Please observe the structure of the page, when you add your content. Please use references where possible. Remember to find the relevant page. For example, if your observation is about Sources, please use that page, instead of posting your content here.

What is already known

  • Person to Person Transmission (close contact). [1]
    • Droplet infection
    • Cross-contamination of hands
  • Fomites. [1]
  • No evidence of vertical (mother-child) transmission. [1]
  • Potential of SARS-CoV2 to survive in aerosol. [2]

Feacal-oral transmission?

Observations

  • Diarrhoea is a common symptom of COVID19. [1]

Analysis and interpretation

  • The question raises, whether we should anticipate transmission routes as observed with SARS (via sewage overflow and aerosols)

Consequences for action

  • Study faecal-oral transmission routes as risk factors for COVID19

Practical Risk of Aerosols

Observations

  • SARS-CoV2 stability in aerosol was experimentally tested, where authors measure the viability of virus on surfaces, after aerosol nebulizing [2]

Analysis and interpretation

  • Does 'viability on surface' mean that the virus is still (biologically) infectious? I would be hesitant to extrapolate the findings of Doremalen to that conclusion.

Consequences for action

  • Further study infectiousness of aerosols, for example in ferret models?

Topic 3

Observations

Analysis and interpretation

Consequences for action

References

  1. 1.0 1.1 1.2 1.3 Rothan, Hussin A., and Siddappa N. Byrareddy. "The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak." Journal of Autoimmunity (2020): 102433.
  2. 2.0 2.1 van Doremalen, Neeltje, et al. "Aerosol and surface stability of HCoV-19 (SARS-CoV-2) compared to SARS-CoV-1." medRxiv (2020).