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=31 December 2019=
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=2019=
* WHO Reports
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==[[Covid November 2019|November]]==
**At the close of 2019, the WHO China Country Office was informed of pneumonia of unknown cause, detected in the city of Wuhan in Hubei province, China. According to the authorities, some patients were operating dealers or vendors in the Huanan Seafood market.
+
A confirmed case of the novel coronavirus emerged on 17 November 2019, according to 13 March 2020 reports of official Chinese government sources,<ref name="original_report">[https://www.scmp.com/news/china/society/article/3074991/coronavirus-chinas-first-confirmed-covid-19-case-traced-back China’s first confirmed Covid-19 case traced back to November 17. South China Morning Post. Josephine Ma. Published: 8:00am, 13 Mar, 2020]</ref> but was not recognized at that time. There may have been earlier patients; the search for them continues.<ref name="msn.com">The first COVID-19 case originated on November 17, according to Chinese officials searching for 'Patient Zero'. [https://www.msn.com/en-us/news/world/the-first-covid-19-case-originated-on-november-17-according-to-chinese-officials-searching-for-patient-zero/ar-BB119fWJ Business Insider.  Isaac Scher 3/13/2020.] </ref><ref name="theguardian.com">Davidson, Helen (13 March 2020).|First Covid-19 case happened in November, China government records show – report. [https://www.theguardian.com/world/2020/mar/13/first-covid-19-case-happened-in-november-china-government-records-show-repor The Guardian. ISSN 0261-3077]. Retrieved 15 March 2020.</ref><ref name="newsweek.com">Walker, James (14 March 2020). China Traces Coronavirus to First Confirmed Case, Nearly Identifying 'Patient Zero'. [https://www.newsweek.com/china-traces-coronavirus-back-first-confirmed-patient-zero-1492327 Newsweek]. Retrieved 14 March 2020.</ref>
Staying in close contact with national authorities, WHO began monitoring the situation and requested further information on the laboratory tests performed and the different diagnoses considered.
 
  
=4 January 2020=
+
==[[Covid December 2019|December]] 27 Cases==
* WHO announced it would work across its 3 levels – country office, regional office and HQ – to track the situation and share details as they emerged.  
+
The first known patient started experiencing symptoms on 1 December 2019. He had not been to the Huanan Seafood Wholesale Market of Wuhan. No epidemiological link could be found between this case and later cases.<ref name="auto1">Wuhan seafood market may not be source of novel virus spreading globally. [https://www.sciencemag.org/news/2020/01/wuhan-seafood-market-may-not-be-source-novel-virus-spreading-globally# Science. By Jon Cohen. Jan. 26, 2020 , 11:25 PM]</ref><ref> Who is 'patient zero' in the coronavirus outbreak? BBC. [https://www.bbc.com/future/article/20200221-coronavirus-the-harmful-hunt-for-covid-19s-patient-zero By Fernando Duarte 24th February 2020]</ref>
* China has reported to WHO a cluster of #pneumonia cases —with no deaths— in Wuhan, Hubei Province 🇨🇳 . Investigations are underway to identify the cause of this illness.
 
  
=5 January=
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Between 8 and 18 December 2019, seven cases later diagnosed as COVID19 were documented; two of them were linked with the Huanan Seafood Wholesale Market; five were not.<ref>Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia. 29 January 2020; [https://www.nejm.org/doi/full/10.1056/NEJMoa2001316 New England Journal of Medicine. vol0. doi=10.1056/NEJMoa2001316.pmid=31995857]</ref>
* WHO published its risk assessment and advice and reported on the status of patients and the public health response by national authorities to the cluster of pneumonia cases in Wuhan.  
 
  
=9 January=
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Chinese state broadcaster CCTV reported in a broadcast airing on 12 January 2020 that a "new viral outbreak was first detected in the city of Wuhan, China, on 12 December 2019". <ref name="auto25">Chinese scientists identify the 'Wuhan Virus'. Screening continues on Thai-bound flights. [https://thethaiger.com/hot-news/tourism/chinese-scientists-identify-the-wuhan-virus-screening-continues-on-thai-bound-flights access-date=8 February 2020]</ref>
* ECDC RRA [https://www.ecdc.europa.eu/en/publications-data/pneumonia-cases-possibly-associated-novel-coronavirus-wuhan-china Pneumonia cases possibly associated with a novel coronavirus in Wuhan, China]
 
** "Considering there is no indication of human-to-human transmission and no cases detected outside of China, the likelihood of introduction to the EU is considered to be low, but cannot be excluded."
 
  
=10 January=
+
Studies are performed to further identify the virus. <ref>Identification of a novel coronavirus causing severe pneumonia in human: a descriptive study. doi=10.1097/CM9.0000000000000722. pmid=32004165. [https://journals.lww.com/cmj/Abstract/publishahead/Identification_of_a_novel_coronavirus_causing.99423.aspx Chinese Medical Journal. 11 February 2020]</ref>
* Developed with reference to other coronaviruses, such as SARS and MERS, WHO issued a tool for countries to check their ability to detect and respond to a novel coronavirus.
 
* This information is to help with identifying main gaps, assessing risks and planning for additional investigations, response and control actions.
 
  
=12 January=
+
According to a post at ''China Youth Daily'', Wuhan Fifth Hospital gastroenterology director Lu Xiaohong reported suspected infection by hospital staff on 25 December.<ref>Before Zhong Nanshan spoke, the doctor in Wuhan issued an outbreak alert to a nearby school. [https://mp.weixin.qq.com/s/IzzCnz4Yr2jEIYZePiu_ow Wang Jiaxing. January 28, 2020]</ref>
* China shares the genetic sequence of the novel coronavirus, which will be very important for other countries as they develop specific diagnostic kits.
 
* Whole genome sequences for the novel #coronavirus (2019-nCoV) from the Chinese authorities were shared with WHO and have also been submitted by Chinese authorities to the GISAID platform so that they can be accessed by public health authorities, laboratories and researchers. [http://pic.twitter.com/wmtGfI4dWl pic.twitter.com/wmtGfI4dWl]
 
  
=13 January=
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A cluster of patients late December is linked to the Wuhan Food Market. At that stage, there are already several Previous patients without any known connection to that market, but in he subsequent months, the Wuhan Market Cluster will fuel theories of this being the ‘ground zero’ of the epidemic.<ref name="auto31">An Outbreak of NCIP (2019-nCoV) Infection in China — Wuhan, Hubei Province, 2019−2020. [http://weekly.chinacdc.cn/en/article/id/e3c63ca9-dedb-4fb6-9c1c-d057adb77b57 1 January 2020.China CDC Weekly. volume=2.issue=5;pages=79–80]</ref>
* Officials confirmed a case of the novel coronavirus in Thailand. It was not unexpected that cases of the novel coronavirus would emerge outside of China and reinforces why WHO calls for active monitoring and preparedness in other countries.
 
* On 13 January 2020, the #Thailand’s Ministry of Public Health @pr_moph reported the first imported case of lab-confirmed novel #coronavirus (2019-nCoV) from #Wuhan, #China https://t.co/Wr6VZTnCj2
 
  
=18 January=
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Other clusters appear, also in Chinese health care facilities. A whistleblower ophthalmologist is disciplined in public, and forced to work with COVID19 patients. He is subsequently infected and dies of the complications. <ref name="auto22">Chinese Coronavirus Whistleblower Li Wenliang Dies of the Disease [https://www.caixinglobal.com/2020-02-07/chinese-coronavirus-whistleblower-dies-101512456.html – Caixin Global.] </ref><ref name="auto27"> The Chinese doctor who tried to warn about coronavirus. [https://www.bbc.com/news/world-asia-china-51364382 Link]. </ref>
* ECDC informs countries
 
** 300 000 Passengers/month EU <--> China
 
** Novel coronavirus circulates in China
 
** 2 cases ex China in Thailand; 1 in Japan
 
**Returning travelers with fever should consult a physician & inform of China visit
 
* WHO
 
* Case def, lab guidance, case management
 
  
=21 January=
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By the end of December 2019, 27 suspected cases in total, seven of which were in critical condition and 18 were stable, two of which were on the verge of being discharged soon.<ref name="auto26">China investigates SARS-like virus as dozens struck by pneumonia. [https://www.dw.com/en/china-investigates-sars-like-virus-as-dozens-struck-by-pneumonia/a-51843861 31 December 2019. Deutsche Welle]</ref> The Wuhan Municipal Health Committee reported to the WHO that 27 people had been diagnosed with pneumonia of unknown cause.<ref name="auto28">Cite web|url=https://promedmail.org/promed-post/|title=Promed Post – ProMED-mail|access-date=2020-02-08|archive-url=https://web.archive.org/web/20200205085608/https://promedmail.org/promed-post/|archive-date=2020-02-05|url-status=live</ref>
* WHO Joint Mission to China
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Early investigations into the cause of the pneumonia ruled out seasonal influenza, SARS, Middle East respiratory syndrome and bird flu.<ref name="Hui14Jan2020">The continuing epidemic threat of novel coronaviruses to global health – the latest novel coronavirus outbreak in Wuhan, China. [https://www.ijidonline.com/article/S1201-9712(20)30011-4/pdf International Journal of Infectious Diseases. volume=91|issue=|pages=264–266|doi=10.1016/j.ijid.2020.01.009|pmid=31953166|issn=1201-9712]</ref><ref name="CDC6Jan2020">Pneumonia of Unknown Cause in China – Watch – Level 1, Practice Usual Precautions – [https://wwwnc.cdc.gov/travel/notices/watch/pneumonia-china Travel Health Notices. 6 January 2020]</ref>
** The delegation observed and discussed active surveillance processes, temperature screening at Wuhan Tianhe airport, laboratory facilities, infection prevention and control measures at Zhongnan hospital and its associated fever clinics, and the deployment of a test kit to detect the virus.
 
** The delegation also discussed public communication efforts and China's plan to expand the case definition for the novel coronavirus, which will build a clearer picture of the spectrum of severity of the virus.
 
** At the end of the visit, the Chinese Government released the primers and probes used in the test kit for the novel coronavirus to help other countries detect it. Chinese experts also shared a range of protocols that will be used in developing international guidelines, including case definitions, clinical management protocols and infection control.
 
  
=22 January=
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HongKong decides that "any suspected cases including the presentation of fever and acute respiratory illness or pneumonia, and travel history to Wuhan within 14 days before onset of symptoms, we will put the patients in isolation."<ref name="auto19">Hong Kong takes emergency steps as a mystery 'pneumonia' infects 27 in Wuhan. [https://www.scmp.com/news/china/politics/article/3044050/mystery-illness-hits-chinas-wuhan-city-nearly-30-hospitalised 31 December 2019. South China Morning Post]</ref> WHO reports this outbreak on 31 December 2019 and monitors the follow up closely.
* [https://www.ecdc.europa.eu/en/publications-data/risk-assessment-outbreak-acute-respiratory-syndrome-associated-novel-coronavirus ECDC RRA COVID19] (#1)
 
** the potential impact of 2019-nCoV outbreaks is high;
 
** further global spread is likely;
 
** there is currently a moderate likelihood of infection for EU/EEA travellers visiting Wuhan;
 
** there is a high likelihood of case importation into countries with the greatest volume of people travelling to and from Wuhan (i.e. countries in Asia);
 
** there is a moderate likelihood of detecting cases imported into EU/EEA countries;
 
** adherence to appropriate infection prevention and control practices, particularly in healthcare settings in EU/EEA countries with direct links to Wuhan, means that the likelihood of a case reported in the EU resulting in secondary cases within the EU/EEA is low.
 
  
=23 January=
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=2020=
* On 22-23 February, the WHO Director General convened the Emergency Committee to consider the outbreak of the novel coronavirus in China, with cases also reported in the Republic of Korea, Japan, Thailand and Singapore.
+
==[[Covid January 2020|January]] - 9,826 cases==
* Several Committee members considered it still too early to declare a Public Health Emergency of International Concern (PHEIC), given its restrictive and binary nature. Among other recommendations, the Committee advised that it be recalled in approximately 10 days
+
This month, the number of cases will increase from 44 to 9,826 and will spread from China to 15 other countries, including France, Germany, Italy and UK.
 +
[[File:Covid19 January 2020.jpg|thumb]]
  
=25 January=
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Like HongKong, Taiwan and Singapore also implement health precautions in the first week of January: arrivals on direct flights from Wuhan are being screened for flu-like symptoms on the tarmac in Taipei before they can disembark.
* ECDC informs countries
+
China is clearly sensoring public reports of the disease, and publicly reprimands whistleblowers.
** Wuhan outbreak evolves rapidly
 
** Cases in 9 other countries outside China
 
** Person to Person spread likely
 
* WHO
 
** Launch of free online introductory course on the novel coronavirus
 
  
=26 January =
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WHO (first) and ECDC (4 days later) publish risk assessments of the situation. <Ref name="ECDCRRA">Pneumonia cases possibly associated with a novel coronavirus in Wuhan, China. [https://www.ecdc.europa.eu/en/publications-data/pneumonia-cases-possibly-associated-novel-coronavirus-wuhan-china ECDC. RRA. 9 January 2020]</ref>. Remarkable is that ECDC states "Considering there is no indication of human-to-human transmission and no cases detected outside of China, the likelihood of introduction to the EU is considered to be low, but cannot be excluded.", despite knowing that previous severe coronavirus infections (SARS, MERS) emerging in humans have all transmitted from person to person.
* [https://www.ecdc.europa.eu/en/publications-data/risk-assessment-outbreak-acute-respiratory-syndrome-associated-novel-0 ECDC RRA COVID19] (#2)
 
** the potential impact of 2019-nCoV outbreaks is high;
 
** further global spread is likely;
 
** there is currently a moderate likelihood of infection for EU/EEA citizens residing in or visiting Wuhan, Hubei province, China;
 
** there is a high likelihood of further case importation into countries with the greatest volume of people who have travelled from Wuhan, Hubei Province (i.e. countries in Asia);
 
** there is a moderate likelihood of further case importation into EU/EEA countries;
 
** adherence to appropriate infection prevention and control practices, particularly in healthcare settings in EU/EEA countries with direct links to Hubei, means that the likelihood of a case detected in the EU resulting in secondary cases within the EU/EEA is low;
 
** the impact of the late detection of an imported case in an EU/EEA country without the application of appropriate infection prevention and control measures would be high, therefore in such a scenario the risk of secondary transmission in the community setting is estimated to be very high
 
  
=30 January=
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WHO issues its first guidance on the novel coronavirus <Ref name="WHO first tool">National capacities review tool for a novel coronavirus. [https://www.who.int/publications-detail/national-capacities-review-tool-for-a-novelcoronavirus WHO technical guidance. 9 January 2020. Publication] </ref> to help countries check their ability to detect and respond to a novel coronavirus, identifying main gaps, assessing risks and planning for additional investigations, response and control actions. China starts sharing the genetic code of the virus.
* [https://www.who.int/news-room/detail/30-01-2020-statement-on-the-second-meeting-of-the-international-health-regulations-(2005)-emergency-committee-regarding-the-outbreak-of-novel-coronavirus-(2019-ncov) WHO declares: 2019-nCoV = PHEIC]
+
ECDC updates countries (on 18 January) and mentions the interconnection with China (300 000 Passengers/month EU <--> China); they advise to identify possible cases among returning travelers.
** Temporary recommendations under IHR
+
WHO manages to get a large (200+) joint mission to China, to assess the situation. Such external assessment in China is unprecedented and facilitated sharing of knowledge and tools.
** Acknowledging that cases have been reported in five WHO regions in one month, the Committee noted that early detection, isolating and treating cases, contact tracing and social distancing measures – in line with the level of risk – can all work to interrupt virus spread.
 
  
=31 January=
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ECDC states on 21 January that there is a moderate likelihood of detecting cases imported into EU/EEA countries, yet that “the likelihood of a case reported in the EU resulting in secondary cases within the EU/EEA is low”. Four days later, ECDC reports that the outbreak evolves rapidly and that person to person spread is likely. WHO struggles in calling this a Public Health Emergency of International Concern (PHEIC), because of the international legal consequences.
* [https://www.ecdc.europa.eu/en/publications-data/risk-assessment-outbreak-acute-respiratory-syndrome-associated-novel-1 ECDC RRA COVID19] (#3)
 
** the potential impact of 2019-nCoV outbreaks is high;
 
** the likelihood of infection for EU/EEA citizens residing in or visiting Hubei province is estimated to be high;
 
** the likelihood of infection for EU/EEA citizens in other Chinese provinces is moderate and will increase;
 
** there is a moderate-to-high likelihood of additional imported cases in the EU/EEA;
 
** the likelihood of observing further limited human-to-human transmission within the EU/EEA is estimated as very low to low if cases are detected early and appropriate infection prevention and control (IPC) practices are implemented, particularly in healthcare settings in EU/EEA countries;
 
** assuming that cases in the EU/EEA are detected in a timely manner and that rigorous IPC measures are applied, the likelihood of sustained human-to-human transmission within the EU/EEA is currently very low to low;
 
** the late detection of an imported case in an EU/EEA country without the application of appropriate infection prevention and control measures would result in the high likelihood of human-to-human transmission, therefore in such a scenario, the risk of secondary transmission in the community setting is estimated to be high.
 
  
=1 February=
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On 26 January, ECDC follows its first Risk Assessment with the advice that “the impact of the late detection of an imported case in an EU/EEA country without the application of appropriate infection prevention and control measures would be high, therefore in such a scenario the risk of secondary transmission in the community setting is estimated to be very high”. This urges all countries to focus fully on containment. Four days later, WHO calls it a PHEIC, while all 5 regions have now been affected.
* ECDC informs countries
 
** 16 cases in EU (5 countries), with local transmission
 
** China takes unprecedented control measures
 
** Potential impact of 2019-nCoV is high
 
** Moderate-High likelihood of more imported cases in EU
 
** Likelihood of human-human transmission in EU is low if early detection of cases and adherence to appropriate IPC practices are implemented, in particular in health care settings
 
  
=3 February=
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==[[Covid February 2020|February]] - 85,203 cases==
* Rapid Communication Eurosurveillance
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This month, the pandemic (even when WHO refuses to categorize it as such) will grow from 9826 to 85,203 cases (growth factor 8.5).
** 38 labs in 24 EU countries had COVID19 tests available
+
[[File:Covid February 2020 Global.jpg|thumb]]
** Availability of primers/probes, positive controls and personnel were main implementation barriers
 
  
=5 February=
+
Early February, there are 16 cases in 5 EU countries with local transmission. China takes unprecedented control measures. ECDC still advises that risk of person to person transmission in EU countries is low, provided that all imported cases are detected promptly, isolated and all their contacts traced and quarantined. In 24 EU countries, 38 labs had COVID19 tests available, yet availability of primers/probes, positive controls and personnel were main implementation barriers.
* Global community asks for US$675 million to help protect vulnerable countries from the outbreak
 
  
=8 February=
+
ECDC publishes “[https://www.ecdc.europa.eu/en/publications-data/guidelines-use-non-pharmaceutical-measures-delay-and-mitigate-impact-2019-ncov Guidelines for the use of non-pharmaceutical measures to delay and mitigate the impact of 2019-nCoV]”. This includes surgical masks for care providers of suspect COVID19 cases and those with extensive public contact. Few countries at that moment adapt the advice to provide masks to professionals with extensive public contact, though that will change in May and June. In addition, ECDC states that “school children are considered to be one of the main drivers of respiratory virus spread in the community”, though it is not yet known how much nCoV2 transmission will occur among children. “Proactive school closures may be considered if there is ongoing transmission of 2019-nCoV in an area”. Countries like the Netherlands contradict this advice by stating that children do not contribute significantly to COVID19 transmission (though no evidence at that time would support such policy advice).
* ECDC informs countries
 
** 9 EU countries with cases (31)
 
  
=10 February=
+
Meanwhile, WHO steps up the warnings to other countries, as it views the complacency of many as a threat to effective pandemic control. On 11 February, Director General Dr. Tedros says that every country should take this virus very seriously. He is losing sleep over it, and he expects that every government should lose sleep over it. This virus should be seen as 'public health enemy nr 1'. "There is a window of opportunity. If we lose it, we will regret it. You need to hit hard, fast".  
* ECDC publishes “[https://www.ecdc.europa.eu/en/publications-data/guidelines-use-non-pharmaceutical-measures-delay-and-mitigate-impact-2019-ncov Guidelines for the use of non-pharmaceutical measures to delay and mitigate the impact of 2019-nCoV]”
+
At that moment, carnaval celebrations are about to start in many countries including the Netherlands, and in March it will be discovered that allowing carnaval was a major factor in accelerating the exponential spread.  
** Hand Hygiene
 
** Respiratory Hygiene (“Cough Etiquette”)
 
** Face Masks & Respirators
 
*** In Health care: Surgical mask for suspected COVID19 cases. FFP masks for HCW during assessment & management
 
*** In other high exposures: Surgical masks for care providers of suspect COVID19 cases and those with extensive public contact
 
*** In Community: By individuals with respiratory symptoms before seeking medical attention
 
** Other PPE:
 
*** HCW caring for COVID19, especially when aerosol-generating procedures.
 
** Social distancing
 
*** Voluntary isolation of COVID19 cases in the community.
 
*** Close contacts: Isolation at home & active daily monitoring
 
*** Casual contacts: Self-monitoring
 
** Schools:
 
*** school children are considered to be one of the main drivers of respiratory virus spread in the community. It is not yet known how much nCoV2 transmission will occur among children
 
*** proactive school closures may be considered if there is ongoing transmission of 2019-nCoV in an area.
 
  
=11 February=
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The UN activates WHO-led Crisis Management Team (with executive director dr Mike Ryan), bringing together WHO, OCHA, IMO, UNICEF, ICAO, WFP, FAO, the World Bank and several UN Secretariat departments.
* Novel coronavirus disease named COVID-19
 
  
=12 February=
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ECDC publishes further guidance and advises to recognize the community as a partner, and to develop an understanding of community perceptions, promote community debriefing, dialogue and a culture of shared learning. Also, ECDC urges countries to roll-out primary testing capacity to local clinical and diagnostic laboratories. For some countries, such as the Netherlands, restricted testing capacity will be a major obstacle in addressing the pandemic effectively, at least until June. Other countries, including Germany, Iceland, find ways to rapidly roll out diagnostic capacity.
* Research and innovation forum sets priorities for COVID-19 research
 
** More than 400 experts and funders met at WHO’s Geneva HQ to accelerate research to stop the COVID-19 outbreak. Featuring updates from the frontlines of the response in China, the meeting addressed issues such as: developing easy-to-apply diagnostics, accelerating existing vaccine candidates and preventing infection
 
* UN activates WHO-led Crisis Management Team
 
** The Crisis Management Team (CMT) mechanism brings together WHO, OCHA, IMO, UNICEF, ICAO, WFP, FAO, the World Bank and several UN Secretariat departments.
 
** The CMT will be managed by the Executive Director of WHO Health Emergencies Programme, Dr Mike Ryan. It will help WHO focus on the health response while the other agencies will bring their expertise to bear on the wider social, economic and developmental implications of the outbreak
 
  
=13 February=
+
ECDC underlines that during the containment phase, extensive tracing and risk assessment of contacts of probable and confirmed cases detected in EU/EEA countries is required in order to minimize the further spread and to strengthen the evidence base on the characteristics and transmission pattern of the disease. Suspected, probable or confirmed cases of COVID19 should be reported to the public health authorities and managed in accordance with national guidance and/or WHO’s patient management guidelines.  
* ECDC publishes “[https://www.ecdc.europa.eu/en/publications-data/guidance-community-engagement-public-health-events-caused-communicable-disease Guidance on community engagement for public health events caused by communicable disease threats in the EU/EEA]”:
+
In several countries, the pandemic is politicized and China (and Chinese people) are blamed. WHO strongly responds: "We must be guided by solidarity, not stigma. The greatest enemy we face is not the virus itself; it’s the stigma that turns us against each other. We must stop stigma and hate.“ (Dr. Tedros)
** Through all three phases of the preparedness cycle
 
**# Recognise the community as a partner
 
**# Develop an understanding of community perceptions
 
**# Optimise communications with at-risk communities
 
**# Invest in a trusted spokesperson and long-term media relations.  
 
** Anticipation phase
 
**# Map stakeholders and integrate them into preparedness planning
 
**# Develop an accessible and inclusive preparedness and response training program
 
**# Cultivate relationships with communities engaged in disease surveillance
 
**# Engage with pre-existing community networks and infrastructures
 
**# Set a research agenda in collaboration with community partners.  
 
** Response phase
 
**# Coordinate distribution of information, protective equipment and other resources for and with community partners
 
**# If using an all-hazards approach, recognize the special character of infectious disease outbreaks and act accordingly
 
**# Facilitate resolving of possible issues with community-level financial losses.  
 
** Recovery phase
 
**# Integrate and document community engagement in evaluation processes
 
**# Promote community debriefing, dialogue and a culture of shared learning.
 
  
=14 February=
+
In the second half of February, WHO warns that the ‘window of opportunity is narrowing’. WHO publishes guidance on getting workplaces ready for COVID19. By the end of the month, EU has 770 cases, including 18 deaths in 19 countries.
* [https://www.ecdc.europa.eu/sites/default/files/documents/SARS-CoV-2-risk-assessment-14-february-2020.pdf.pdf ECDC RRA COVID19] (#4)
 
** It is important that countries consider the roll-out of primary diagnostic testing capacity to local clinical and diagnostic laboratories.  
 
** Confirmatory testing remains the responsibility of the referral or reference laboratories.
 
** Therefore, positive specimens should still be shipped for second detection assay and possible sequencing to referral or reference laboratories.
 
** During the containment phase, extensive tracing and risk assessment of contacts of probable and confirmed cases detected in EU/EEA countries is required in order to minimize the further spread and to strengthen the evidence base on the characteristics and transmission pattern of the disease.  
 
** Suspected, probable or confirmed cases of COVID19 should be reported to the public health authorities and managed in accordance with national guidance and/or WHO’s patient management guidelines
 
  
=15 February=
+
==[[Covid March 2020|March]] - 797,268 cases==
* ECDC informs countries
+
This month, the global case-counter will advance from 87,024 to 797,268 cases (growth factor of 9.2).
** Further P-P transmission in EU
+
[[File:Covid19 March 2020 Global.jpg|thumb]]
** Hospital associated transmission suspected in 41% of hospitalised Wuhan patients
 
* WHO
 
** "We must be guided by solidarity, not stigma. The greatest enemy we face is not the virus itself; it’s the stigma that turns us against each other. We must stop stigma and hate.“ Dr Tedros
 
  
=17 February=
+
ECDC publishes new guidance and risk assessments. It emphasizes the importance to enhance surveillance, epidemiological investigation, close contact tracing, management of close contacts, immediate case detection and isolation. “There’s no choice but to act now” (WHO, Dr Tedros)
* WHO issues guidance on mass gathering and taking care of ill travellers
+
A shortage of personal protective equipment endangering health workers worldwide
** Based on lessons from H1N1 and Ebola, WHO has outlined planning considerations for organizers of mass gatherings, in light of the COVID-19 outbreak. It has also issued advice on how to detect and take care of ill travellers, who are suspected COVID-19 cases.
 
  
=18 February=
+
The WHO R&D roadmap for COVID-19 outlines research priorities in 9 key areas. These include the natural history of the virus, epidemiology, diagnostics, clinical management, ethical considerations and social sciences, as well as longer-term goals for therapeutics and vaccines.
* WHO has shipped supplies of personal protective equipment to 21 countries.
 
** By the end of this week, 40 countries in Africa and 29 in the Americas are due to have the ability to detect COVID-19
 
  
=21 February=
+
WHO: “All countries must aim to stop transmission and prevent the spread of COVID-19, whether they face no cases, sporadic cases, clusters or community transmission.“ and (finally) calls the COVID19 PHEIC a pandemic on 11 March.
* WHO Director-General warns that the window of opportunity is “narrowing”
 
* Special envoys on COVID-19 selected
 
** Professor Dr Maha El Rabbat, former Minister of Health of Egypt;
 
** Dr David Nabarro, former special adviser to the United Nations Secretary-General
 
** Dr John Nkengasong, Director of the African Centres for Disease Control and Prevention;
 
** Dr Mirta Roses, former Director of the WHO Region of the Americas;
 
** Dr Shin Young-soo, former Regional Director of the WHO Region of the Western Pacific;
 
** Professor Samba Sow, Director-General of the Center for Vaccine Development in Mali.
 
  
=22 February=
+
Europe becomes the epicenter of the pandemic
* ECDC informs countries
 
** Viral shedding expected to be similar to Influenza
 
* WHO
 
** During the past month about 11 000 African health workers have been trained using WHO’s online courses on COVID-19, which are available free of charge in English, French & other languages
 
** WHO’s Director-General and Regional Director for Africa addressed an emergency meeting of ministers of health to agree on a continental strategy for Africa to strengthen preparedness and responses to the COVID-19 outbreak
 
  
= 22 February=
+
WHO keeps insisting that countries should test every suspected case of COVID-19. Meanwhile, countries that have failed to ramp up diagnostic capacity, are forced to prioritize testing. In the Netherlands, this leads on 12 March to the decision to let go of the containment strategy, and to move to mitigation efforts. As a consequence, NL suspends the national obligatory notification of suspect covid cases: the epidemic progresses exponentially as the country struggles to double ICU capacity, while practically suspending all non-essential medical procedures.
* ECDC informs countries
 
** Viral shedding expected to be similar to Influenza
 
* WHO
 
** During the past month about 11 000 African health workers have been trained using WHO’s online courses on COVID-19, which are available free of charge in English, French & other languages
 
** WHO’s Director-General and Regional Director for Africa addressed an emergency meeting of ministers of health to agree on a continental strategy for Africa to strengthen preparedness and responses to the COVID-19 outbreak
 
  
=24 February=
+
COVID19 starts to affect areas in the world that are already plagued by severe humanitarian crises.  
* UN Secretary-General António Guterres met with the WHO Director-General and other WHO leaders, receiving a briefing on COVID-19, Ebola and polio. He expressed great admiration for health workers, including in China, who are working tirelessly to save lives. The UN Secretary-General also stressed that there is no space for stigma and discrimination and said we must be guided by science and human rights-based interventions
+
The UN Secretary-General calls for solidarity, hope and political will.
* A team of experts from WHO and the European Centre for Disease Prevention and Control (ECDC) will focus on: understanding how events developed, learning from the Italian experience and supporting control and prevention efforts by the authorities.
 
* To limit further human to human transmission, WHO experts will provide support in the areas of clinical management, infection prevention and control, surveillance and risk communication.
 
  
=25 February=
+
WHO and FIFA team up on a campaign to kick out coronavirus
* The team of 25 international and Chinese experts travelled to several different provinces, with a small group going to Wuhan, the epicenter of the outbreak.
 
** Among the team's findings was that the epidemic peaked and plateaued between the 23rd of January and the 2nd of February, and has been declining steadily since then. The team also estimates that the measures taken in China have averted a significant number of cases.
 
** In a press conference in Geneva on Tuesday 25 February, Dr Bruce Aylward, the mission's lead, reported back on what China has done, its impact and implications.
 
* The WHO Director-General has repeatedly called for "solidarity, not stigma" to address COVID-19. 
 
** WHO has worked with UNICEF and the International Federation of Red Cross and Red Crescent Societies on a guide to preventing and addressing the social stigma associated with the disease. 
 
** It's vital to fight stigma because it can drive people to hide the illness, not seek health care immediately and discourage them from adopting healthy behaviours. 
 
** This guide includes some tips and messages, as well as dos and don'ts on language when talking about COVID-19.
 
  
=26 February=
+
ECDC Risk Assessment: The risk of severe disease associated with COVID-19 for people in the EU/EEA and the UK is currently considered moderate for the general population and very high for older adults and individuals with chronic underlying conditions. The risk of occurrence of widespread national community transmission of COVID-19 in the EU/EEA and the UK in the coming weeks is moderate if effective mitigation measures are in place and very high if insufficient mitigation measures are in place.
* ECDC publishes Checklist for hospitals preparing for the reception and care of (COVID-19) patients
 
** Elements to be assessed have been divided into the following areas:
 
*** Establishment of a core team and key internal and external contact points
 
*** Human, material and facility capacity
 
*** Communication and data protection
 
*** Hand hygiene, personal protective equipment (PPE), and waste management
 
*** Triage, first contact and prioritisation
 
*** Patient placement, moving of the patients in the facility, and visitor access
 
*** Environmental cleaning
 
*WHO: Get your workplace ready for COVID-19
 
  
=27 February=
+
Several parties in the lower house of Dutch parliament are in favor of forcing pharmaceutical company Roche to release the manufacturing process and recipe of the coronavirus test they make if this is necessary. This would make it possible for tests to be produced in the Netherlands, NOS reports.
* WHO: What every country should be asking itself
+
Some time later, the Switzerland based pharmaceutical company Roche releases the detailed guidelines on how to prepare the lysis buffer fluid for the COVID19 test, after pressure and negotiations with Dutch ministry of health. <Ref>Roche deelt recept van vloeistof voor coronatests alsnog. [https://nos.nl/artikel/2328567-roche-deelt-recept-van-vloeistof-voor-coronatests-alsnog.html NOS News. 27 March 2020]</ref>
** Are we ready for the first case?
+
UK Prime Minister Boris Johnson tests positive for SARS-CoV2.
** Do we have enough medical oxygen, ventilators and other vital equipment?
 
** How will we know if there are cases in other areas of the country?
 
** Do our health workers have the training and equipment they need to stay safe?
 
** Do we have the right measures at airports and border crossings to test people who are sick?
 
** Do our labs have the right chemicals that allow them to test samples?
 
** Are we ready to treat patients with severe or critical disease?
 
** Do our hospitals and clinics have the right procedures to prevent and control infections?
 
** Do our people have the right information? Do they know what the disease looks like?
 
  
=28 February=
+
By the end of this month, there are 797,268 cases globally, including 37,911 reported deaths.
* WHO: What every individual can do to protect themselves and others
 
  
=29 February=
+
==[[Covid April 2020|April]] - 3,133,235 cases ==
* ECDC informs countries
+
This month, the pandemic will expand further globally, to a cumulative of 3,133,235 cases (growth factor this month: 3.9)
** In EU: 770 cases / 18 deaths in 19 countries
+
[[File:Covid19 April 2020 Global.jpg|thumb]]
  
=1 March=
+
UK Prime Minister Boris Johnson is hospitalised with #COVID19 <Ref name="BBC-BJH">[https://www.bbc.com/news/uk-52177125 Coronavirus: PM admitted to hospital over virus symptoms]. BBC News. 6 April 2020. </ref>
* UN releases US$15 million for COVID-19 response
 
  
=2 March=
+
ECDC advises on using face masks in the community - Reducing COVID-19 transmission from potentially asymptomatic or pre-symptomatic people through the use of face masks. <ref>[https://www.ecdc.europa.eu/sites/default/files/documents/COVID-19-use-face-masks-community.pdf ECDC Technical Report. Using face masks in the community - Reducing COVID-19 transmission from potentially asymptomatic or pre-symptomatic people through the use of face masks.8 April 2020.]</ref>
* [https://www.ecdc.europa.eu/en/publications-data/rapid-risk-assessment-outbreak-novel-coronavirus-disease-2019-covid-19-increased ECDC RRA COVID19] (#5)
+
[[File:Facemask-infographic-long-version.png|100px]]
** Immediate activation of national emergency response mechanisms and pandemic preparedness plans to ensure containment and mitigation of COVID-19 with non-pharmaceutical public health measures.
 
** Ensuring the general public is aware of the seriousness of COVID-19. A high degree of population understanding, community engagement and acceptance of the measures put in place (including more stringent social ** distancing) are key in preventing further spread.
 
** Implementation of protocols for COVID-19 laboratory testing, diagnosis, surveillance and treatment.
 
** Enhancement of surveillance, epidemiological investigation, close contact tracing, management of close contacts, immediate case detection and isolation.
 
** Implementation of social distancing (e.g. the suspension of large-scale gatherings and the closure of schools and workplaces) to interrupt the chains of transmission.
 
** Adapted risk communication and provision of adequate personal protective equipment for healthcare workers and rigorous application of infection prevention and control measures in healthcare facilities.
 
** Provision of adequate healthcare capacity to isolate, support and actively treat patients.
 
** Publishes COVID19 case definition ([[Case Definition issues|issues reported]])
 
* WHO:
 
** Publishes COVID19 case definition ([[Case Definition issues|issues reported]])
 
** Mission of WHO experts arrive in Iran
 
** “There’s no choice but to act now” (WHO, Dr Tedros)
 
  
=3 March=
+
By 15 April the German Federal Ministry has agreed with the German States the guiding principle: "to protect all people in Germany as well as possible from the infection". In order to quickly identify infection chains in the future, carry out targeted tests, ensure full contact tracking and provide professional care for those affected, considerable additional personnel capacities are created in the local public health services, at least one team of 5 people per 20,000 inhabitants. Germany has a high test capacity of up to 650,000 tests a week to detect corona infections (PCR tests). The federal government secures additional test capacities for Germany by purchasing test equipment. <Ref> Decision of the Chancellor's telephone switching conference with the heads of government of the federal states on April 15, 2020. [https://www.bundesregierung.de/breg-de/aktuelles/bund-laender-beschluss-1744224 Website of the German Federal Government. Accessed 20 April 2020]</ref>.
* Shortage of personal protective equipment endangering health workers worldwide
+
Meanwhile, officials in the Netherlands express their doubt about the use of contact tracing, and advocate ‘controlled spread of the virus, to achieve group-immunity’. This point of view meets with opposition from outside the public sector, though this does not change the point of view for the remainder of the month. The formal national guidance states that source and contact tracing ‘have no priority’, and that contact tracing is to be restricted to contacts that could transmit COVID to high-risk groups.
  
=5 March=
+
ECDC Published Infographic CONTACT TRACING:
* WHO: Director-General emphasized that the COVID-19 epidemic “can be pushed back, but only with a collective coordinated and comprehensive approach that engages the entire machinery of government.
+
[[File:COVID-19-contact-tracing-infographic_0.png|100px|]]
 +
ECDC publishes the 9th Rapid Risk Assessment that includes public health objectives: "Limit and control virus circulation and transmission in the general population now (flattening the curve) and for the years to come to maintain the number of new SARS-CoV-2 infections at manageable levels for the healthcare system, and possibly allowing for gradual acquisition of population immunity."; this suggests that ECDC has given up the ambition of containment, and joins the member states that aim for group immunity, and 'controlled circulation'.
  
=6 March=
+
By the end of April, the WHO-IHR Emergency Committee met. The Committee unanimously agreed that the outbreak still constitutes a public health emergency of international concern (PHEIC) and offered advice to the Director-General, who declared that the outbreak of COVID-19 continues to constitute a PHEIC.
* WHO publishes [https://www.who.int/blueprint/priority-diseases/key-action/Coronavirus_Roadmap_V9.pdf?ua=1 draft R&D blueprint draft for COVID-19]
 
** The R&D roadmap for COVID-19 outlines research priorities in 9 key areas. These include the natural history of the virus, epidemiology, diagnostics, clinical management, ethical considerations and social sciences, as well as longer-term goals for therapeutics and vaccines.
 
  
=7 March=
+
==[[Covid May 2020|May]] -  6,028,628 cases==
* ECDC informs countries
+
[[File:World covid 1 may 2020.png|thumb]]
** In EU: 4738 cases / 140 deaths in 27 countries
+
The pandemic spread generates growing awareness that deep economic recession may lie ahead. WHO and the European Investment Bank (EIB) will boost cooperation to strengthen public health, the supply of essential equipment, training, and investment in countries most vulnerable to the COVID-19 pandemic. The first phase will address urgent needs and strengthen primary health care in ten African countries.
* WHO
 
** Marking 100 000 cases worldwide
 
  
=8 March=
+
More reports emerge about the correlation between a paediatric inflammatory multisystem syndrome and SARS-CoV-2 infection in children.
* WHO:
 
** Interim guidance on critical preparedness, readiness and response actions
 
  
=9 March=
+
ECDC continues to publish valuable guidance to help countries prepare for contact tracing: "Contact tracing for COVID-19: current evidence, options for scale-up and an assessment of resources needed". Soon thereafter, WHO publishes their contact tracing guidelines. The response among EU countries varies. Germany had already stepped up their contact tracing strategy as well as capacity since mid-April,<Ref> Decision of the Chancellor's telephone switching conference with the heads of government of the federal states on April 15, 2020. [https://www.bundesregierung.de/breg-de/aktuelles/bund-laender-beschluss-1744224 Website of the German Federal Government. Accessed 20 April 2020]</ref>, while being very clear about their strategy: "to protect all people in Germany as well as possible from the infection".  
* WHO: “The rule of the game is: never give up.
+
Other countries, such as the Netherlands, still stated in their online COVID19 guidance that source tracing had no priority and that contact tracing was to be restricted to high-risk populations only. The Dutch parliament debated fiercely with the Prime-Minister Mark Rutte, to understand what the cabinet exactly meant with their strategy of 'maximum control'. The Prime-Minister refused to acknowledge that this was to be interpreted as 'maximum reduction of transmission'. The Prime-Minister responded "We, therefore, opt for maximum control, whereby the virus is kept under control as much as possible. If there are outbreaks, you will start containment." <ref> [https://www.tweedekamer.nl/kamerstukken/plenaire_verslagen/detail/5c92e993-bd8d-4fbc-a287-a055f45174dd Tweede Kamer, 73e vergadering. Woensdag 20 mei 2020] Plenair verslag. Status: gecorrigeerd. </ref>
** “We are not at the mercy of this virus,” said the WHO Director-General at the 9 March media briefing.
 
** All countries must aim to stop transmission and prevent the spread of COVID-19, whether they face no cases, sporadic cases, clusters or community transmission.
 
** “Let hope be the antidote to fear. Let solidarity be the antidote to blame. Let our shared humanity be the antidote to our shared threat"
 
  
= 10 March=
+
ECDC Publishes a 3rd update of the Technical Report "Infection prevention and control and preparedness for COVID-19 in healthcare settings - third update". ECDC also published a Rapid Risk Assessment: Paediatric inflammatory multisystem syndrome and SARS-CoV-2 infection in children.
* ECDC Publishes Discharge criteria for confirmed COVID-19 cases
 
* Answers to questions
 
** What is the duration of SARS-CoV-2 virus shedding in bodily fluids of
 
*** Symptomatic patients after remission of symptoms?
 
*** Asymptomatic patients?
 
** Which tests are available to document the lack of infectivity in a previously diagnosed infection?
 
** What is the longest documented transmission from an asymptomatic person?
 
* WHO:
 
** Provides guidance to help people manage fear, stigma and discrimination during COVID-19
 
** WHO issues schools guidance with UNICEF and IFRC
 
  
=11 March=
+
As more EU countries consider relaxing the lockdown measures, especially allowing the airline industry to pick up speed again, ECDC publishes technical report “COVID-19 Aviation Health Safety Protocol: Guidance for the management of airline passengers in relation to the COVID-19 pandemic", and later, the technical reports “Considerations for travel-related measures to reduce spread of COVID-19 in the EU/EEA” and “Projected baselines of COVID-19 in the EU/EEA and the UK for assessing the impact of de-escalation of measures”
* WHO declares a pandemic
 
  
=12 March=
+
== [[Covid June 2020|June]] - 10,273,424 cases==
* ECDC Publishes [https://www.ecdc.europa.eu/en/publications-data/infection-prevention-and-control-covid-19-healthcare-settings Infection prevention and control for COVID-19 in healthcare settings]
 
** This update addresses the possible limited supply of personal protective equipment (PPE), hand hygiene materials, and environmental hygiene materials for healthcare facilities
 
* [https://www.ecdc.europa.eu/en/publications-data/rapid-risk-assessment-novel-coronavirus-disease-2019-covid-19-pandemic-increased ECDC RRA COVID19] (#6)
 
** Need for immediate targeted action
 
*** Situation similar to China and Italy threatens to occur in other countries within days or weeks
 
** Social distancing
 
*** Immediate isolation of suspect COVID19
 
*** Suspension of mass gathering
 
*** Teleworking
 
*** Closure of schools
 
*** Cordon sanitaire around communities with high transmission
 
** Public awareness & solidarity
 
** IPC in HealthCare
 
** Train HCW who might be asked for support
 
** Surveillance should focus on rapid case detection, shifting to assessing the effectiveness of community measures
 
  
=13 March=
+
On 12 June, the Dutch Government decided that airline travel could commence operations as usual, based on scientific advice from the Dutch Ministry of Health.<ref>[https://www.rijksoverheid.nl/documenten/rapporten/2020/06/12/advies-luchtvaart-covid-19 Kamerbrief Over COVID19 en Luchtvaart.] 12 juni 2020</ref>
* WHO, UN Foundation and partners launch first-of-its-kind COVID-19 Solidarity Response Fund
+
The Dutch Minister of Transport, Public Works and Water Management, together with the Minister for Public Health advise the Dutch parliament that Distancing measures in aeroplanes are not necessary, according to the Considerations on COVID9 by the Ministry of Health. The Considerations on COVID9 by the Ministry of Health do not seem to include such conclusion: on the contrary, they acknowledge that distancing is a key principle in COVID19 prevention. Yet, these considerations fail to include the most relevant conclusion by ECDC on travel-related COVID19 risk: no matter how many preventive measures you take, travel will always increase COVID19 risk. And the fewer measures, the higher the risk. The omission of distancing cannot be compensated by other measures. See also the [[Dutch Discussion on Public transport]].
* Europe becomes the epicenter of the pandemic
 
* Launch of #SafeHands Challenge
 
  
=14 March=
+
== [[Covid July 2020|July]] - 17,298,074 cases ==
* ECDC informs countries
+
The global pandemic is still accelerating. This creates a new thread of confusion in public communication; the difference between 'new cases', 'epidemic growth', 'accelerated transmission', and 'exponential growth', may be commonplace for the numerically educated, yet these concepts are not always well understood.
** In EU: 22 753 cases / 1032 deaths in all countries
+
Dr. Tedros says "We all want this to be over. But the hard reality is that this is far from over."
 +
{{#ev:youtube|h92DDmXBLTs|||||start=50}}
  
=16 March=
+
== [[Covid August 2020|August]] - 25,275,762 cases ==
* WHO: "You cannot fight a fire blindfolded.“
 
** Countries should test every suspected case of COVID-19.
 
** If people test positive, they should be isolated and the people they have been in close contact with up to 2 days before they developed symptoms should be sought out, and those people should be tested too if they show symptoms of COVID-19.
 
** WHO also advises that all confirmed cases, even mild cases, should be isolated in health facilities, to prevent transmission and provide adequate care.
 
** But we recognize that many countries have already exceeded their capacity to care for mild cases in dedicated health facilities.
 
** In that situation, countries should prioritize older patients and those with underlying conditions.
 
  
=17 March=
+
== [[Covid September 2020|September]] ==
* ECDC Publishes Guidance for health system contingency planning during widespread transmission of SARS-CoV-2 with high impact on healthcare services
 
** Approaches on how to increase capacity for managing COVID-19 cases in the context of widespread sustained SARS-CoV-2 transmission
 
* WHO:
 
** New guidance on people affected by humanitarian crises
 
** WHO calls for urgent, aggressive actions to combat COVID-19, as cases soar in South-East Asia Region
 
  
=18 March=
 
* European Medicines Agency (EMA): (Also [[Risk_factors_for_severe_disease|published by WHO]])
 
** On 18 March 2020, EMA published a statement on the use of non-steroidal anti-inflammatories for COVID-19.
 
** There is currently no scientific evidence establishing a link between ibuprofen and worsening of COVID‑19
 
* More than 320 000 learners enrol in online COVID-19 courses
 
* WHO Launch of SOLIDARITY trial
 
  
=19 March=
 
* WHO Regional Office for Africa holds joint COVID-19 media briefing with World Economic Forum
 
** Guidance published: [https://documentcloud.adobe.com/link/track?uri=urn%3Aaaid%3Ascds%3AUS%3A7d6bc5d2-a857-4bd4-a9db-b1a2c8b25e8e Operational considerations for case management of COVID-19 in health facility and community]
 
* UN Secretary-General calls for solidarity, hope and political will
 
  
=20 March=
+
=References=
* WHO: Young people "are not invincible"
+
<References/>
** Speaking at the COVID-19 media briefing, the Director-General said:
 
** "Although older people are the hardest hit, younger people are not spared. Data from many countries clearly show that people under 50 make up a significant proportion of patients requiring hospitalization. Today, I have a message for young people: you are not invincible. This virus could put you in hospital for weeks, or even kill you. Even if you don’t get sick, the choices you make about where you go could be the difference between life and death for someone else. I’m grateful that so many young people are spreading the word and not the virus.“
 
* WHO Health Alert for coronavirus launches on WhatsApp
 
 
 
=21 March=
 
* ECDC informs countries
 
** In EU: 74 362 cases / 3694 deaths in all countries
 
 
 
=23 March=
 
* WHO and FIFA team up on a campaign to kick out coronavirus
 

Latest revision as of 07:08, 18 September 2020

2019

November

A confirmed case of the novel coronavirus emerged on 17 November 2019, according to 13 March 2020 reports of official Chinese government sources,[1] but was not recognized at that time. There may have been earlier patients; the search for them continues.[2][3][4]

December 27 Cases

The first known patient started experiencing symptoms on 1 December 2019. He had not been to the Huanan Seafood Wholesale Market of Wuhan. No epidemiological link could be found between this case and later cases.[5][6]

Between 8 and 18 December 2019, seven cases later diagnosed as COVID19 were documented; two of them were linked with the Huanan Seafood Wholesale Market; five were not.[7]

Chinese state broadcaster CCTV reported in a broadcast airing on 12 January 2020 that a "new viral outbreak was first detected in the city of Wuhan, China, on 12 December 2019". [8]

Studies are performed to further identify the virus. [9]

According to a post at China Youth Daily, Wuhan Fifth Hospital gastroenterology director Lu Xiaohong reported suspected infection by hospital staff on 25 December.[10]

A cluster of patients late December is linked to the Wuhan Food Market. At that stage, there are already several Previous patients without any known connection to that market, but in he subsequent months, the Wuhan Market Cluster will fuel theories of this being the ‘ground zero’ of the epidemic.[11]

Other clusters appear, also in Chinese health care facilities. A whistleblower ophthalmologist is disciplined in public, and forced to work with COVID19 patients. He is subsequently infected and dies of the complications. [12][13]

By the end of December 2019, 27 suspected cases in total, seven of which were in critical condition and 18 were stable, two of which were on the verge of being discharged soon.[14] The Wuhan Municipal Health Committee reported to the WHO that 27 people had been diagnosed with pneumonia of unknown cause.[15] Early investigations into the cause of the pneumonia ruled out seasonal influenza, SARS, Middle East respiratory syndrome and bird flu.[16][17]

HongKong decides that "any suspected cases including the presentation of fever and acute respiratory illness or pneumonia, and travel history to Wuhan within 14 days before onset of symptoms, we will put the patients in isolation."[18] WHO reports this outbreak on 31 December 2019 and monitors the follow up closely.

2020

January - 9,826 cases

This month, the number of cases will increase from 44 to 9,826 and will spread from China to 15 other countries, including France, Germany, Italy and UK.

Covid19 January 2020.jpg

Like HongKong, Taiwan and Singapore also implement health precautions in the first week of January: arrivals on direct flights from Wuhan are being screened for flu-like symptoms on the tarmac in Taipei before they can disembark. China is clearly sensoring public reports of the disease, and publicly reprimands whistleblowers.

WHO (first) and ECDC (4 days later) publish risk assessments of the situation. [19]. Remarkable is that ECDC states "Considering there is no indication of human-to-human transmission and no cases detected outside of China, the likelihood of introduction to the EU is considered to be low, but cannot be excluded.", despite knowing that previous severe coronavirus infections (SARS, MERS) emerging in humans have all transmitted from person to person.

WHO issues its first guidance on the novel coronavirus [20] to help countries check their ability to detect and respond to a novel coronavirus, identifying main gaps, assessing risks and planning for additional investigations, response and control actions. China starts sharing the genetic code of the virus. ECDC updates countries (on 18 January) and mentions the interconnection with China (300 000 Passengers/month EU <--> China); they advise to identify possible cases among returning travelers. WHO manages to get a large (200+) joint mission to China, to assess the situation. Such external assessment in China is unprecedented and facilitated sharing of knowledge and tools.

ECDC states on 21 January that there is a moderate likelihood of detecting cases imported into EU/EEA countries, yet that “the likelihood of a case reported in the EU resulting in secondary cases within the EU/EEA is low”. Four days later, ECDC reports that the outbreak evolves rapidly and that person to person spread is likely. WHO struggles in calling this a Public Health Emergency of International Concern (PHEIC), because of the international legal consequences.

On 26 January, ECDC follows its first Risk Assessment with the advice that “the impact of the late detection of an imported case in an EU/EEA country without the application of appropriate infection prevention and control measures would be high, therefore in such a scenario the risk of secondary transmission in the community setting is estimated to be very high”. This urges all countries to focus fully on containment. Four days later, WHO calls it a PHEIC, while all 5 regions have now been affected.

February - 85,203 cases

This month, the pandemic (even when WHO refuses to categorize it as such) will grow from 9826 to 85,203 cases (growth factor 8.5).

Covid February 2020 Global.jpg

Early February, there are 16 cases in 5 EU countries with local transmission. China takes unprecedented control measures. ECDC still advises that risk of person to person transmission in EU countries is low, provided that all imported cases are detected promptly, isolated and all their contacts traced and quarantined. In 24 EU countries, 38 labs had COVID19 tests available, yet availability of primers/probes, positive controls and personnel were main implementation barriers.

ECDC publishes “Guidelines for the use of non-pharmaceutical measures to delay and mitigate the impact of 2019-nCoV”. This includes surgical masks for care providers of suspect COVID19 cases and those with extensive public contact. Few countries at that moment adapt the advice to provide masks to professionals with extensive public contact, though that will change in May and June. In addition, ECDC states that “school children are considered to be one of the main drivers of respiratory virus spread in the community”, though it is not yet known how much nCoV2 transmission will occur among children. “Proactive school closures may be considered if there is ongoing transmission of 2019-nCoV in an area”. Countries like the Netherlands contradict this advice by stating that children do not contribute significantly to COVID19 transmission (though no evidence at that time would support such policy advice).

Meanwhile, WHO steps up the warnings to other countries, as it views the complacency of many as a threat to effective pandemic control. On 11 February, Director General Dr. Tedros says that every country should take this virus very seriously. He is losing sleep over it, and he expects that every government should lose sleep over it. This virus should be seen as 'public health enemy nr 1'. "There is a window of opportunity. If we lose it, we will regret it. You need to hit hard, fast". At that moment, carnaval celebrations are about to start in many countries including the Netherlands, and in March it will be discovered that allowing carnaval was a major factor in accelerating the exponential spread.

The UN activates WHO-led Crisis Management Team (with executive director dr Mike Ryan), bringing together WHO, OCHA, IMO, UNICEF, ICAO, WFP, FAO, the World Bank and several UN Secretariat departments.

ECDC publishes further guidance and advises to recognize the community as a partner, and to develop an understanding of community perceptions, promote community debriefing, dialogue and a culture of shared learning. Also, ECDC urges countries to roll-out primary testing capacity to local clinical and diagnostic laboratories. For some countries, such as the Netherlands, restricted testing capacity will be a major obstacle in addressing the pandemic effectively, at least until June. Other countries, including Germany, Iceland, find ways to rapidly roll out diagnostic capacity.

ECDC underlines that during the containment phase, extensive tracing and risk assessment of contacts of probable and confirmed cases detected in EU/EEA countries is required in order to minimize the further spread and to strengthen the evidence base on the characteristics and transmission pattern of the disease. Suspected, probable or confirmed cases of COVID19 should be reported to the public health authorities and managed in accordance with national guidance and/or WHO’s patient management guidelines. In several countries, the pandemic is politicized and China (and Chinese people) are blamed. WHO strongly responds: "We must be guided by solidarity, not stigma. The greatest enemy we face is not the virus itself; it’s the stigma that turns us against each other. We must stop stigma and hate.“ (Dr. Tedros)

In the second half of February, WHO warns that the ‘window of opportunity is narrowing’. WHO publishes guidance on getting workplaces ready for COVID19. By the end of the month, EU has 770 cases, including 18 deaths in 19 countries.

March - 797,268 cases

This month, the global case-counter will advance from 87,024 to 797,268 cases (growth factor of 9.2).

Covid19 March 2020 Global.jpg

ECDC publishes new guidance and risk assessments. It emphasizes the importance to enhance surveillance, epidemiological investigation, close contact tracing, management of close contacts, immediate case detection and isolation. “There’s no choice but to act now” (WHO, Dr Tedros) A shortage of personal protective equipment endangering health workers worldwide

The WHO R&D roadmap for COVID-19 outlines research priorities in 9 key areas. These include the natural history of the virus, epidemiology, diagnostics, clinical management, ethical considerations and social sciences, as well as longer-term goals for therapeutics and vaccines.

WHO: “All countries must aim to stop transmission and prevent the spread of COVID-19, whether they face no cases, sporadic cases, clusters or community transmission.“ and (finally) calls the COVID19 PHEIC a pandemic on 11 March.

Europe becomes the epicenter of the pandemic

WHO keeps insisting that countries should test every suspected case of COVID-19. Meanwhile, countries that have failed to ramp up diagnostic capacity, are forced to prioritize testing. In the Netherlands, this leads on 12 March to the decision to let go of the containment strategy, and to move to mitigation efforts. As a consequence, NL suspends the national obligatory notification of suspect covid cases: the epidemic progresses exponentially as the country struggles to double ICU capacity, while practically suspending all non-essential medical procedures.

COVID19 starts to affect areas in the world that are already plagued by severe humanitarian crises. The UN Secretary-General calls for solidarity, hope and political will.

WHO and FIFA team up on a campaign to kick out coronavirus

ECDC Risk Assessment: The risk of severe disease associated with COVID-19 for people in the EU/EEA and the UK is currently considered moderate for the general population and very high for older adults and individuals with chronic underlying conditions. The risk of occurrence of widespread national community transmission of COVID-19 in the EU/EEA and the UK in the coming weeks is moderate if effective mitigation measures are in place and very high if insufficient mitigation measures are in place.

Several parties in the lower house of Dutch parliament are in favor of forcing pharmaceutical company Roche to release the manufacturing process and recipe of the coronavirus test they make if this is necessary. This would make it possible for tests to be produced in the Netherlands, NOS reports. Some time later, the Switzerland based pharmaceutical company Roche releases the detailed guidelines on how to prepare the lysis buffer fluid for the COVID19 test, after pressure and negotiations with Dutch ministry of health. [21] UK Prime Minister Boris Johnson tests positive for SARS-CoV2.

By the end of this month, there are 797,268 cases globally, including 37,911 reported deaths.

April - 3,133,235 cases

This month, the pandemic will expand further globally, to a cumulative of 3,133,235 cases (growth factor this month: 3.9)

Covid19 April 2020 Global.jpg

UK Prime Minister Boris Johnson is hospitalised with #COVID19 [22]

ECDC advises on using face masks in the community - Reducing COVID-19 transmission from potentially asymptomatic or pre-symptomatic people through the use of face masks. [23] Facemask-infographic-long-version.png

By 15 April the German Federal Ministry has agreed with the German States the guiding principle: "to protect all people in Germany as well as possible from the infection". In order to quickly identify infection chains in the future, carry out targeted tests, ensure full contact tracking and provide professional care for those affected, considerable additional personnel capacities are created in the local public health services, at least one team of 5 people per 20,000 inhabitants. Germany has a high test capacity of up to 650,000 tests a week to detect corona infections (PCR tests). The federal government secures additional test capacities for Germany by purchasing test equipment. [24]. Meanwhile, officials in the Netherlands express their doubt about the use of contact tracing, and advocate ‘controlled spread of the virus, to achieve group-immunity’. This point of view meets with opposition from outside the public sector, though this does not change the point of view for the remainder of the month. The formal national guidance states that source and contact tracing ‘have no priority’, and that contact tracing is to be restricted to contacts that could transmit COVID to high-risk groups.

ECDC Published Infographic CONTACT TRACING: COVID-19-contact-tracing-infographic 0.png ECDC publishes the 9th Rapid Risk Assessment that includes public health objectives: "Limit and control virus circulation and transmission in the general population now (flattening the curve) and for the years to come to maintain the number of new SARS-CoV-2 infections at manageable levels for the healthcare system, and possibly allowing for gradual acquisition of population immunity."; this suggests that ECDC has given up the ambition of containment, and joins the member states that aim for group immunity, and 'controlled circulation'.

By the end of April, the WHO-IHR Emergency Committee met. The Committee unanimously agreed that the outbreak still constitutes a public health emergency of international concern (PHEIC) and offered advice to the Director-General, who declared that the outbreak of COVID-19 continues to constitute a PHEIC.

May - 6,028,628 cases

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The pandemic spread generates growing awareness that deep economic recession may lie ahead. WHO and the European Investment Bank (EIB) will boost cooperation to strengthen public health, the supply of essential equipment, training, and investment in countries most vulnerable to the COVID-19 pandemic. The first phase will address urgent needs and strengthen primary health care in ten African countries.

More reports emerge about the correlation between a paediatric inflammatory multisystem syndrome and SARS-CoV-2 infection in children.

ECDC continues to publish valuable guidance to help countries prepare for contact tracing: "Contact tracing for COVID-19: current evidence, options for scale-up and an assessment of resources needed". Soon thereafter, WHO publishes their contact tracing guidelines. The response among EU countries varies. Germany had already stepped up their contact tracing strategy as well as capacity since mid-April,[25], while being very clear about their strategy: "to protect all people in Germany as well as possible from the infection". Other countries, such as the Netherlands, still stated in their online COVID19 guidance that source tracing had no priority and that contact tracing was to be restricted to high-risk populations only. The Dutch parliament debated fiercely with the Prime-Minister Mark Rutte, to understand what the cabinet exactly meant with their strategy of 'maximum control'. The Prime-Minister refused to acknowledge that this was to be interpreted as 'maximum reduction of transmission'. The Prime-Minister responded "We, therefore, opt for maximum control, whereby the virus is kept under control as much as possible. If there are outbreaks, you will start containment." [26]

ECDC Publishes a 3rd update of the Technical Report "Infection prevention and control and preparedness for COVID-19 in healthcare settings - third update". ECDC also published a Rapid Risk Assessment: Paediatric inflammatory multisystem syndrome and SARS-CoV-2 infection in children.

As more EU countries consider relaxing the lockdown measures, especially allowing the airline industry to pick up speed again, ECDC publishes technical report “COVID-19 Aviation Health Safety Protocol: Guidance for the management of airline passengers in relation to the COVID-19 pandemic", and later, the technical reports “Considerations for travel-related measures to reduce spread of COVID-19 in the EU/EEA” and “Projected baselines of COVID-19 in the EU/EEA and the UK for assessing the impact of de-escalation of measures”

June - 10,273,424 cases

On 12 June, the Dutch Government decided that airline travel could commence operations as usual, based on scientific advice from the Dutch Ministry of Health.[27] The Dutch Minister of Transport, Public Works and Water Management, together with the Minister for Public Health advise the Dutch parliament that Distancing measures in aeroplanes are not necessary, according to the Considerations on COVID9 by the Ministry of Health. The Considerations on COVID9 by the Ministry of Health do not seem to include such conclusion: on the contrary, they acknowledge that distancing is a key principle in COVID19 prevention. Yet, these considerations fail to include the most relevant conclusion by ECDC on travel-related COVID19 risk: no matter how many preventive measures you take, travel will always increase COVID19 risk. And the fewer measures, the higher the risk. The omission of distancing cannot be compensated by other measures. See also the Dutch Discussion on Public transport.

July - 17,298,074 cases

The global pandemic is still accelerating. This creates a new thread of confusion in public communication; the difference between 'new cases', 'epidemic growth', 'accelerated transmission', and 'exponential growth', may be commonplace for the numerically educated, yet these concepts are not always well understood. Dr. Tedros says "We all want this to be over. But the hard reality is that this is far from over."

August - 25,275,762 cases

September

References

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  2. The first COVID-19 case originated on November 17, according to Chinese officials searching for 'Patient Zero'. Business Insider. Isaac Scher 3/13/2020.
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  4. Walker, James (14 March 2020). China Traces Coronavirus to First Confirmed Case, Nearly Identifying 'Patient Zero'. Newsweek. Retrieved 14 March 2020.
  5. Wuhan seafood market may not be source of novel virus spreading globally. Science. By Jon Cohen. Jan. 26, 2020 , 11:25 PM
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  10. Before Zhong Nanshan spoke, the doctor in Wuhan issued an outbreak alert to a nearby school. Wang Jiaxing. January 28, 2020
  11. An Outbreak of NCIP (2019-nCoV) Infection in China — Wuhan, Hubei Province, 2019−2020. 1 January 2020.China CDC Weekly. volume=2.issue=5;pages=79–80
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  17. Pneumonia of Unknown Cause in China – Watch – Level 1, Practice Usual Precautions – Travel Health Notices. 6 January 2020
  18. Hong Kong takes emergency steps as a mystery 'pneumonia' infects 27 in Wuhan. 31 December 2019. South China Morning Post
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  21. Roche deelt recept van vloeistof voor coronatests alsnog. NOS News. 27 March 2020
  22. Coronavirus: PM admitted to hospital over virus symptoms. BBC News. 6 April 2020.
  23. ECDC Technical Report. Using face masks in the community - Reducing COVID-19 transmission from potentially asymptomatic or pre-symptomatic people through the use of face masks.8 April 2020.
  24. Decision of the Chancellor's telephone switching conference with the heads of government of the federal states on April 15, 2020. Website of the German Federal Government. Accessed 20 April 2020
  25. Decision of the Chancellor's telephone switching conference with the heads of government of the federal states on April 15, 2020. Website of the German Federal Government. Accessed 20 April 2020
  26. Tweede Kamer, 73e vergadering. Woensdag 20 mei 2020 Plenair verslag. Status: gecorrigeerd.
  27. Kamerbrief Over COVID19 en Luchtvaart. 12 juni 2020